Don’t let bloating, gas, and gastrointestinal discomfort effect your quality of life. Try Benegut – an innovative, natural, gut health ingredient based on the extract of Shiso leaves (Perilla frutescens). It has an immediate and perceptible balancing effect on bowel comfort.

Benegut guarantees highest, consistent and defined quality. It is scientifically proven, IP protected, and frequently used in food supplements. Benegut is marketed in Europe and Australia under the brand name Nutrigut.

Benegut® helps to reduce:*

    • Bloating
    • Feeling of fullness
    • Gastrointestinal rumbling
    • Abdominal discomfort

Human study results confirm:

Benegut is able to reduce gastrointestinal discomfort. In a double blind, randomized, placebo-controlled, parallel design human study, 50 healthy people, ages 30-70, were administered capsules containing 150 mg proprietary Perilla frutescens leaf extract twice a day, for 4 weeks. Results demonstrated that Benegut is able to reduce gastrointestinal discomfort.

BMC Complementary and Alternative Medicine Logo

Perilla Extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study

Buchwald-Werner et al. BMC Complementary and Alternative Medicine 2014, 14:173

Full text link

Tekno Scienze publisher (TKS) publishing logo

Perilla Frutescens targets intestinal permeability. In vitro study on TNF-α stress-induced barrier dysfunction in intestinal epithelial cells

Buchwald-Werner et al. Agro FOOD Industry Hi Tech – vol. 27(5) – September/October 2016

Full text link


Appearance Beige powder with characteristic odor
Solubility Freely soluble in 100 g / L in water
Loss on drying < 5.0 %
Particle size > 80 % < 180 µm
Bulk density 0.2 - 0.6 g /ml
Tapped density 0.4 - 0.8 g / ml
pH 4.6 - 5.6 10 % water solution
Foreign matter Not detected
Total Polyphenols ≥ 0.57 %
Rosmarinic acid ≥ 0.05 %
Special Flavonoid Fraction ≥ 0.18 %
Vicenin-2 ≥ 0.007 %
Methyleugenol (Phenylpropene) not detected (Limit: 0.1 ppm)
Myristicin (Phenylpropene) not detected (Limit: 0.1 ppm)
Perillaketone (Terpenoid) not detected (Limit: 0.1 ppm)
Pesticides (EC) No 396/2005 complies
Heavy metals (EC) No 1881/2006 complies
Microbiology: Ph. Eur. 8ed. Cat. 5.1.4 complies


Benegut® – Science & Application

Benegut, the proprietary Perilla frutescens leaf extract, contains a specific ratio of selected flavonoids, particularly Vicenin 2, in combination with rosmarinic acid. All active compounds naturally found in Perilla.

Benegut uniquely combines prokinetic and antispasmodic as well as anti-inflammatory effects, leading to an immediate, perceptible relief of gastrointestinal discomfort.

In vitroex vivo and human studies demonstrated that Benegut is able to balance bowel movement by interacting with the neurological system and therefore can counteract the effects of psychosocial factors, such as e.g. stress causing altered gut physiology leading to gastrointestinal discomfort.

It has proven prebiotic effects, particularly to support growth of L. plantarum, B. lactis, B. longum infantis and B. longum longum. Due to its proven prebiotic effects it is an ideal candidate for blends with probiotic and / or other prebiotic ingredients.

Benegut is the first non-probiotic, innovative ingredient that improves gastrointestinal discomfort and prevents disease linked to gut irregularity and inflammation, such as irritable bowel syndrome.

Benegut is high quality, sustainable, IP protected, natural ingredient, approved to be used in food supplements in Europe and the U.S. It is a water soluble fine beige powder with a recommended daily dosage of 300 mg.

Benegut® – Origin & Production

Benegut is obtained by water extraction out of Perilla frutescens (L.) leaves. Perilla frutescens is a member of the family Lamiaceae and is an annual edible herbaceous plant, native to Asia.  Globally, it is well known as spice of the Japanese cuisine, where it is named Shiso.

Beneguts production facility and manufacturing process comply with the highest international standards of safety, hygiene and quality control: ISO-9001:2008, ISO-22000:2005 and is GMP certified for food supplements. Benegut complies with highest quality and traceability standards, completed by phytochemical characterization and stability data.

Women holding Benegut signature picture

Benegut® supports concepts for:*

Gut health
– to improve gastrointestinal comfort

– to maintain and improve digestion during aging

– to reduce bloating and support a flat belly

Sports nutrition
– to regulate digestion during sports


* These statements have not been evaluated by FDA and EFSA.
The product is not intended to diagnose, treat or cure any disease.