Bluenesse® – Caffeine Synergizer

Bluenesse® is a scientifically proven natural ingredient to support focus, alertness, and cognitive performance, while maintaining a calm and good mood. Furthermore, it helps to balance the stress hormone cortisol. It provides perceptible effects within one hour after intake, which are still measurable after three hours. Consumers can feel the difference. Bluenesse® and caffeine are the perfect fit, supporting tangible nootropic effects while Bluenesse® balances anxiety and due to its longer duration of efficacy impedes the caffeine crash.

The perfect fit for sports & esports nutritional products and energy drinks to support healthy, reliable performance

Fact sheet Bluenesse®


  • Quick onset of effects
  • Nootropic effects to support focus, alertness and performance
  • Supports exercise performance, and focus to win

Even better

  • 5 hours effect
  • Robust calming and anti-anxiety efficacy, balancing caffeine intake associated anxiety, agitation and sleep disturbances
  • Improves the ability to cope with stress, by combating daily stressors and cortisol; supporting healthy fat metabolism
Lemon balm field in Germany

Unique Quality:

  • Only the highest quality leaves of a special lemon balm breeding line are used for Bluenesse® to ensure the nootropic effects
  • Bluenesse® is a proprietary Melissa officinalis (L.) extract, controlled by bioassay-guided efficacy testing and standardized on >6% rosmarinic acid and muscarinic M1 receptor affinity. This is a new dimension of quality control

Mode of action

  • Balancing of neurotransmitter (GABA, Acetylcholine, and Dopamine) concentrations in the brain supporting effective and quick communication between nerve cells in the brain.
  • Reduction of stress-induced cortisol level
  • Antioxidant
  • Effective dosage: 300 mg

Science behind

  • Several scientific studies demonstrated that Bluenesse® combines the traditional calming and mood enhancing effects with beneficial effects to support cognitive performance, particularly focus, alertness and memory (1), (2)
  • Patented


  • Natural food ingredient, obtained by solvent-free, gentle water extraction, out of ID verified lemon balm leaves
  • Complies with highest quality, stability and traceability standards
  • Caffeine-free, stimulant-free, doping substances-free, no hang-over


  • Bluenesse® is feasible for all kinds of foods or supplements delivery formats
  • It is water-soluble and has a peasant herbal taste. Its effective dosage of 300 mg can be easily formulated in ready to drink powders, shots, gels, gummies, and protein powders
  • It works well in dairy products, bars and cookies

These statements have not been evaluated by FDA and EFSA. The product is not intended to diagnose, treat or cure any disease.