Don’t let bloating, gas, and gastrointestinal discomfort effect your quality of life. Try Nutrigut – an innovative, natural, gut health ingredient based on the extract of Shiso leaves (Perilla frutescens). It has an immediate and perceptible balancing effect on bowel comfort.

Nutrigut guarantees highest, consistent and defined quality. It is scientifically proven, IP protected, and frequently used in food supplements. It is scientifically proven, IP protected, and frequently used in food supplements. Nutrigut is the brand name used for Benegut in Europe and Australia.

Nutrigut® helps to reduce:*

    • Bloating
    • Feeling of fullness
    • Gastrointestinal rumbling
    • Abdominal discomfort

Human study results confirm:

Nutrigut is able to reduce gastrointestinal discomfort. In a double blind, randomized, placebo-controlled, parallel design human study, 50 healthy people, ages 30-70, were administered capsules containing 150 mg proprietary Perilla frutescens leaf extract twice a day, for 4 weeks. Results demonstrated that Benegut is able to reduce gastrointestinal discomfort.

Products featuring Nutrigut®

Related scientific publications

Perilla Extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study

Buchwald-Werner et al. BMC Complementary and Alternative Medicine 2014, 14:173

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Tekno Scienze publisher (TKS) publishing logo

Perilla Frutescens targets intestinal permeability. In vitro study on TNF-α stress-induced barrier dysfunction in intestinal epithelial cells

Buchwald-Werner et al. Agro FOOD Industry Hi Tech – vol. 27(5) – September/October 2016

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Appearance Beige powder with a characteristic odor
Solubility Freely soluble in 100 g / L in water
Loss on drying < 5.0 %
Particle size > 80 % < 180 µm
Bulk density 0.2 - 0.6 g /ml
Tapped density 0.4 - 0.8 g / ml
pH 4.6 - 5.6 10 % water solution
Foreign matter Not detected
Total Polyphenols ≥ 0.57 %
Rosmarinic acid ≥ 0.05 %
Special Flavonoid Fraction ≥ 0.18 %
Vicenin-2 ≥ 0.007 %
Methyleugenol (Phenylpropene) not detected (Limit: 0.1 ppm)
Myristicin (Phenylpropene) not detected (Limit: 0.1 ppm)
Perillaketone (Terpenoid) not detected (Limit: 0.1 ppm)
Pesticides (EC) No 96/2005 complies
Heavy metals (EC) No 1881/2006 complies
Microbiology: Ph. Eur. 8ed. Cat. 5.1.4 complies


Nutrigut® – Science & Application

Nutrigut, the proprietary Perilla frutescens leaf extract, contains a specific ratio of selected flavonoids, particularly Vicenin 2, in combination with rosmarinic acid; all active compounds naturally found in Perilla.

Nutrigut uniquely combines prokinetic and antispasmodic as well as anti-inflammatory effects, leading to an immediate, perceptible relief of gastrointestinal discomfort.

In vitro, ex vivo and human studies demonstrated that Nutrigut is able to balance bowel movement by interacting with the neurological system and therefore can counteract the effects of psychosocial factors, such as e.g. stress causing altered gut physiology leading to gastrointestinal discomfort.

It has proven prebiotic effects, particularly to support growth of L. plantarum, B. lactis, B. longum infantis and B. longum longum. Due to its proven prebiotic effects it is an ideal candidate for blends with probiotic and / or other prebiotic ingredients.

Nutrigut is the first non-probiotic, innovative ingredient that improves gastrointestinal discomfort and prevents disease linked to gut irregularity and inflammation, such as irritable bowel syndrome.

Nutrigut is high quality, sustainable, IP protected, natural ingredient, approved to be used in food supplements in Europe and the U.S. It is a water soluble fine beige powder with a recommended daily dosage of 300 mg.

Nutrigut® – Origin & Production

Nutrigut is obtained by water extraction out of Perilla frutescens (L.) leaves. Perilla frutescens is a member of the family Lamiaceae and is an annual edible herbaceous plant, native to Asia.  Globally, it is well known as spice of the Japanese cuisine, where it is named Shiso.

Nutrigut’s production facility and manufacturing process comply with the highest international standards of safety, hygiene and quality control: ISO-9001:2008, ISO-22000:2005 and is GMP certified for food supplements. Nutrigut complies with highest quality and traceability standards, completed by phytochemical characterization and stability data.

Women holding Benegut signature picture

Nutrigut® supports concepts for:*

Gut health
– to improve gastrointestinal comfort

– to maintain and improve digestion during aging

– to reduce bloating and support a flat belly

Sports nutrition
– to regulate digestion during sports


* These statements have not been evaluated by FDA and EFSA. The product is not intended to diagnose, treat or cure any disease.